A pan-African pathogen genomics data sharing platform to support disease outbreaks

In a recent post in The Conversation, SANBI Director Professor Alan Christoffels and Africa CDC Pathogen Genomics Programme Lead Dr Sofonias Tessema explain the need for a repository for pathogen data sharing between African countries:

Infectious disease outbreaks in African countries are, unfortunately, all too common. Ebola in the Democratic Republic of the Congo or Uganda; Marburg virus in Guinea or Equatorial Guinea; cholera in Malawi; malaria and tuberculosis are among them.

These diseases do not respect human-made or porous borders. So it’s essential that scientists in Africa are able to generate and share critical data on the pathogens in time to inform public-health decisions.

Genomic sequencing technologies are powerful tools in this kind of work. They enable scientists to decode the genetic material of diseases and create biological “fingerprints” to investigate and track the pathogens that cause those diseases. This information aids in developing diagnostics, treatments and vaccines. It also helps public health authorities to guide and prepare their public health systems for effective outbreak detection and response.

Tackling infectious diseases across countries and continents requires many complex, overlapping and broad interventions. One of those is a common repository where countries, public health authorities and their scientists can share information about diseases and the pathogens that cause them. They can then collaborate around the shared data. These kinds of platforms exist in many high-income countries. But the African region lags behind.

Read more at The Conversation or read the paper that Prof Christoffels (together with SANBI research Peter van Heusden, Dr Tessema and others) wrote on this topic and here Prof Christoffels discuss this work on the SABC website.