As a research institute, the Director of SANBI reports through the faculty of Natural Sciences to the University of the Western Cape.  SANBI staff are made up of a diverse group of research scientists, technical and administrative staff who all contribute to a dynamic productive working environment.

Academic staff are tasked with conducting research in their laboratories, securing funding, student graduations and capacity development.  The computing infrastructure is maintained and developed by a team of technical staff while administrators ensure the smooth running of daily operations.